five

Crystal Structure of mGluR5 in complex with Fenobam at 2.65 A

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal Structure of mGluR5 in complex with Fenobam at 2.65 A Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(3-chlorophenyl)-3-(3-methyl-5-oxidanylidene-4~{H}-imidazol-2-yl)urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Christopher, J.A, Orgovan, Z, Congreve, M, Dore, A.S, Errey, J.C, Marshall, F.H, Mason, J.S, Okrasa, K, Rucktooa, P, Serrano-Vega, M.J, Ferenczy, G.G, Keseru, G.M. Deposit date: 2018-01-08 Release date: 2018-03-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures. J.Med.Chem., 62, 2019
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2018-01-08
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