Crystal structure of KAT6A in complex with inhibitor CTx-648 (PF-9363)
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Crystal structure of KAT6A in complex with inhibitor CTx-648 (PF-9363) Descriptor: 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide, Histone acetyltransferase KAT6A, ZINC ION Authors: Greasley, S.E, Johnson, E, Brodsky, O. Deposit date: 2022-06-17 Release date: 2023-07-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Targeting KAT6A/KAT6B dependencies in breast cancer with a novel selective, orally bioavailable KAT6 inhibitor, CTx-648/PF-9363 To Be Published
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2022-06-17
