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Micafungin microevolution in Candida auris reveals resistance development without in vivo fitness compromise

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Figshare2025-10-14 更新2026-04-28 收录
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In this study, we applied a microevolution approach to generate multiple micafungin resistant strains using two clinical C. auris isolates (AR0381 from clade II and AR0387 from clade I) that originated from patients with distinct clinical manifestations. We then examined both the impact and reproducibility of micafungin resistance development in these two isolates.

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2025-10-14
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