Endothelial Cell Senescence Stimulates Amyloid-β Phagocytosis and Barrier Function of Microglia Leading to Attenuation of Cognitive Impairment in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
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Our results reveal that EC senescence enhances microglial phenotype shift into neuroprotective phenotype with increases in phagocytic and barrier functions, and propose that an apparently paradoxical idea may contribute to the development of a novel therapeutic strategy for AD. 4 samples
创建时间：
2023-12-17
