The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1
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https://www.ncbi.nlm.nih.gov/sra/SRP193717
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资源简介:
We demonstrate that global effects of TRIM71 on the cellular transcriptome of mouse embryonic stem cells (mESCs) are largely attributable to its RNA binding activity, and map the transcriptome-wide targets of wild-type TRIM71, NHL domain mutant TRIM71, and RING domain mutant TRIM71. Overall design: CRAC (crosslinking and analysis of cDNAs) analysis of Trim71 wild-type, NHL mutant and RING mutant in mouse embryonic stem cells.
创建时间:
2019-10-31



