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Crystal structure of the BRAF (R509H) kinase domain monomer bound to Vemurafenib

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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资源简介:
Crystal structure of the BRAF (R509H) kinase domain monomer bound to Vemurafenib Descriptor: N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf Authors: Wu, Y, Gavathiotis, E. Deposit date: 2014-12-24 Release date: 2016-08-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.994 Å) Cite: An integrated model of RAF inhibitor action predicts inhibitor activity against oncogenic BRAF signaling Cancer Cell, 30, 2016
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2014-12-24
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