Human BACE-1 COMPLEX WITH AYH011
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Human BACE-1 COMPLEX WITH AYH011 Descriptor: (1R,3S)-3-[1-(acetylamino)-1-methylethyl]-N-[(1S,2S,4R)-1-benzyl-5-(butylamino)-2-hydroxy-4-methyl-5-oxopentyl]cyclohexanecarboxamide, Beta-secretase 1 Authors: Rondeau, J.-M. Deposit date: 2009-10-07 Release date: 2010-05-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2009-10-07
