TIRR inhibits the 53BP1-p53 complex to alter cell fate

NIAID Data Ecosystem2026-03-12 收录

细胞命运调控

p53信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP281233 数据链接链接失效反馈

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资源简介：

RNA sequencing in TIRR-KO cells to understand which cellular pathways are influenced by TIRR

创建时间：

2021-08-31

Table_1_17β-Estradiol Promotes Apoptosis in Airway Smooth Muscle Cells Through CD38/SIRT1/p53 Pathway.XLSX

细胞凋亡机制

p53信号通路

17β-Estradiol (E2) is the major estrogen secreted by the premenopausal ovary and shows dual effects on cell apoptosis under pathological conditions. E2 was previously shown to increase CD38 mRNA and p

NIAID Data Ecosystem260

Epidermal overexpression of ∆NLef1 leads to deregulation of epidermal stem cell fate

细胞命运调控

毛囊发育分子机制

In adult K14ΔNLef1 mouse, the overexpression of ∆NLef1, a B-catenin dominat negative, in basal keratinocytes leads to the conversion of hair follicles into multilayered epithelial cysts and ectopic se

NIAID Data Ecosystem60

Zinc Finger 280B Regulates sGCα1 and p53 in Prostate Cancer Cells

前列腺癌

p53信号通路

The Zinc Finger (ZNF) 280B protein was identified as an unexpected target of an shRNA designed for sGCα1. Further analysis showed that these two proteins are connected in another way, with 280B up-reg

NIAID Data Ecosystem50

IRF2 is a master regulator of human keratinocyte stem cell fate

细胞命运调控

皮肤角质形成细胞

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem80

The small molecule compound P2 in HCT116p53-/- and HCT116p53+/+ cells

癌症基因表达分析

p53信号通路

Global gene expression in HCT116p53-/- and HCT116p53+/+ cells HCT116p53-/- and p53+/+ were untreated and treated with P2 small molecule compound at 25 microM, total RNA was isolated and gene expressio

NIAID Data Ecosystem50

TIRR inhibits the 53BP1-p53 complex to alter cell fate

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