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Data belonging to the publication: "Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension"

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4TU.ResearchData2022-07-07 更新2026-04-23 收录
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https://data.4tu.nl/articles/_/20237562/1
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资源简介:
This study couples a Finite Element model for arterial mechanics to an Agent-Based model for mechanosensitive Notch signaling among vascular smooth muscle cells to predict the phenotype of these cells under hypertension, a loss of residual stresses in the artery, and manipulations of the Notch signaling pathway. This dataset contains the codes for the Finite Element model, the Agent-Based model and the coupling between them, as well as the raw data generated by these models.

本研究将用于动脉力学分析的有限元模型(Finite Element Model),与针对血管平滑肌细胞间机械敏感性Notch信号通路(Notch signaling)的基于智能体的模型(Agent-Based Model)进行耦合,旨在预测高血压状态下、动脉残余应力缺失时,以及Notch信号通路受到干预时此类细胞的表型特征。本数据集包含该有限元模型、基于智能体的模型及其耦合代码,同时涵盖上述模型生成的原始数据。
提供机构:
Baaijens, Frank; Ristori, Tommaso; Asten, van, Jordy; Loerakker, Sandra; Lally, Caitríona; Sahlgren, Cecilia; Nolan, David
创建时间:
2022-07-07
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