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BAP1 enhances Polycomb repression counteracting widespread H2AK119ub1 deposition and chromatin condensation

NIAID Data Ecosystem2026-03-12 收录

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蛋白质印迹

数据链接：

https://data.mendeley.com/datasets/yv6c2s8jtc 数据链接链接失效反馈

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资源简介：

Raw data of western blots and Imaging data and analyses used in Conway et al.

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创建时间：

2021-06-18

组蛋白修饰与肿瘤发生

表观遗传调控

In this study, our results support a functional divergence between H3K36me2 and H3K36me3 and their non-redundant roles in H3K36M-driven oncogenesis Overall design: 17 ChIP-seq samples, 3 RNA-seq sampl

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Epigenetic basis for monocyte dysfunction in acute-on-chronic liver failure and alcoholic hepatitis [RNA-seq]

肝病相关单核细胞功能障碍

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BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

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DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

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甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

ExtFig1B_WB_PA_R1-R2-R3_LG386-390-397.tif

蛋白质印迹

病毒感染分子机制

Protein lysates of Xrn1 knock out (ko) A549 cells infected with WT PR8 or PR8-PA(∆X), or mock infected, were probed with antibodies against PR8 PA or beta-tubulin as a loading control.

Figshare2023-01-19 更新10

Transcriptional Dynamics of Skeletal Muscle in Obesity (PRJCA023478)

肥胖相关转录组学

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Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

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BAP1 enhances Polycomb repression counteracting widespread H2AK119ub1 deposition and chromatin condensation

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