Supplementary data: Acetate-producing probiotic in APOE4 mice

Supplementary data for "A precision acetate-producing probiotic alters brain metabolism, reduces neuroinflammation, and modifies brain gene expression in pre-symptomatic APOE4 mice" (Gut Microbes, under review). Supplementary_Table_S1.xlsx: CosMx spatial transcriptomics differential expression (Figs. 7–8) POCE-MRS_Glx4_Labeling.xlsx: in vivo POCE-MRS Glx4 labeling, APOE3 vs APOE4 (Fig. 2, Table 1) Brain_GCMS_Metabolomics.xlsx: brain GC–MS metabolomics (Figs. 3–4, Table 2) Fecal_16S_Microbiome.xlsx: fecal 16S rRNA ASV table, taxonomy and sample metadata (Fig. 5) IBA1_Immunohistochemistry.xlsx: IBA1 immunohistochemistry, cortex and hippocampus (Fig. 6, Table 3)