首页/数据集/E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration

E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration

NIAID Data Ecosystem2026-05-01 收录

酶复合体突变研究

代谢酶动力学

数据链接：

https://www.rcsb.org/structure/3LQ2 数据链接链接失效反馈

官方服务：

资源简介：

E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration

应用场景：

创建时间：

2023-09-06

酶结构解析

代谢酶动力学

Structure of bovine glutamate dehydrogenase in the unliganded state Descriptor: Glutamate dehydrogenase 1, mitochondrial Authors: Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P

Protein Data Bank Japan2025-06-11 更新40

The K m , V max and CL int for CYP1A2 and IC 50 of baicalin on CYP1A2 in HLMs (n = 28).

代谢酶动力学

药物相互作用评估

The Km, Vmax and CLint for CYP1A2 and IC50 of baicalin on CYP1A2 in HLMs (n = 28).

NIAID Data Ecosystem30

Kinetic parameters derived from DMC- O -glucuronidation by UGT1A1 and HeLa1A1 cell lysate.

代谢酶动力学

醛氧化反应

Kinetic parameters derived from DMC-O-glucuronidation by UGT1A1 and HeLa1A1 cell lysate.

NIAID Data Ecosystem30

Theoretical Characterization of Substrate Access/Exit Channels in the Human Cytochrome P450 3A4 Enzyme: Involvement of Phenylalanine Residues in the Gating Mechanism

代谢酶动力学

分子动力学模拟

The human cytochrome P450 3A4 mono-oxygenates ∼50% of all drugs. Its substrates/products enter/leave the active site by access/exit channels. Here, we perform steered molecular dynamics simulations, p

NIAID Data Ecosystem40

Parameters of ligand interactions with CYP3A4 determined by steady-state and time-resolved LRET*.

代谢酶动力学

配体-酶相互作用

*Life-time measurements were performed at nearly-saturating ligand concentrations, which were equal to 100 µM, 2.5 µM, 50 µM and 100 µM for ANF, bromocriptine, cholesterol, and testosterone, respectiv

Figshare2015-12-02 更新30

E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration

资源简介：

相关数据集