Measurement of the total protein concentration, antioxidant activity, lipid peroxidation and formation of prostaglandins E2 of the tissue homogenates.

This experiment consists of the negative control group (Group 1), the complex control group (Group 2), the lesion control group (Group 3), the reference group pre-treated with 5.790×10−5 M/kg of omeprazole (Group 4) and the experimental groups (Groups 5–8) which received 1.091×10−5, 2.181×10−5, 4.362×10−5 and 8.724×10−5 M/kg of the zinc (II) complex as a pre-treatment. All values are expressed as mean ± standard error mean. Mean difference is significant at the p<0.05 level (one-way between groups ANOVA with post-hoc analysis). *significant when compared to the ulcer control group (Group 3). #significant when compared to the reference control group (Group 4). NO, nitric oxide; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; MDA, Malondialdehyde; PGE-2, prostaglandins E2.