Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.
收藏PubMed Central1995-11-07 更新2026-05-02 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC40698/
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资源简介:
The gene encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) has been proposed recently as a candidate gene for the mouse severe combined immune deficiency (scid) locus. We have used a partial cDNA clone for human DNA-PKcs to map the mouse homologue using a large interspecific backcross panel. We found that the mouse gene for DNA-PKcs does not recombine with scid, consistent with the hypothesis that scid is a mutation in the mouse gene for DNA-PKcs. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1995-11-07



