Transcriptome sequencing data analysis of Bacillus subtilis NCIB 3610 treated with DMSO and AQCA

In our study, we discovered that AQCA (Anthraquinone-2-carboxylic acid) effectively degrades Bacillus subtilis NCIB 3610 biofilms, a finding of significant research importance. To investigate the underlying mechanisms, we performed transcriptome sequencing of wild-type biofilms treated with either DMSO (control) or AQCA. Statistical analysis of gene expression (P < 0.05) revealed that AQCA treatment led to significant changes: 184 genes were upregulated, while 503 genes were downregulated by at least twofold compared to the DMSO control group. Overall design: mRNA profiles of Bacillus subtilis NCIB 3610 wild type biofilms treated with DMSO and AQCA