Differential response to rotator cuff tear in C57BL/6J mice and MRL/MpJ mice

We report RNA sequencing data from the infraspinatus muscles of 3-month old male C57BL/6J (Jackson Labs stock 000664) or MRL/MpJ mice (Jackson Labs stock 000486). Mice underwent a full-thickness infraspinatus tenectomy and denervation, and four weeks later muscles were collected for analysis. Comparisons are made to control male mice of the same strains who did not undergo infraspinatus tenectomy and denervation. Differential expression of mRNAs were evaluated between the infraspinatus muscles of C57BL/6J and MRL/MpJ mice that were either subjected to a infraspinatus tenectomy and denervation or who were unoperated controls.本研究报道了3月龄雄性C57BL/6J小鼠（杰克逊实验室品系编号000664）或MRL/MpJ小鼠（杰克逊实验室品系编号000486）的冈下肌（infraspinatus muscle）RNA测序数据。实验小鼠接受全层冈下肌腱切断术及去神经支配处理，术后四周采集其肌肉组织用于后续分析。本研究以未接受该手术的同品系雄性小鼠作为对照开展组间比较，并对接受冈下肌腱切断术及去神经支配处理、或未接受手术的C57BL/6J与MRL/MpJ小鼠冈下肌组织中的信使RNA（messenger RNA, mRNA）差异表达水平进行了评估。