首页/数据集/Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

NIAID Data Ecosystem2026-05-10 收录

疫苗免疫学

抗体功能分析

数据链接：

https://immport.org/shared/study/SDY2343 数据链接链接失效反馈

官方服务：

资源简介：

To define the specific humoral profiles that track with protective immunity against disease and infection after NVX-CoV2373 vaccination in primates and to define whether similar functional humoral profiles are elicited in humans.

应用场景：

创建时间：

2025-10-30

老年免疫反应研究

疫苗免疫学

Introduction: Each year, a disproportionate number of the total seasonal influenza-related hospitalizations (90%) and deaths (70%) occur among adults who are >65 years old. Inflammasome activation has

NIAID Data Ecosystem70

Transcriptional atlas of the cytokine drivers and cellular contributors mediating enhanced SARS-CoV-2 lung pathology in hamsters after non-protective immunization. Transcriptional atlas of the cytokine drivers and cellular contributors mediating enhanced SARS-CoV-2 lung pathology in hamsters after non-protective immunization

疫苗免疫学

呼吸道疾病转录组学

Since December 2019, the novel human Coronavirus SARS-CoV-2 has spread globally, causing millions of deaths. Unprecedented efforts have enabled development and authorization of a range of vaccines, wh

NIAID Data Ecosystem50

Effect of Antigen, Type I IFN and STING Signaling on CD8 T Cell Immunity With Adenoviral Vaccines. Mus musculus

疫苗免疫学

CD8T细胞免疫反应

Recombinant adenoviral vectors (rAds), derived from distinct species with different serotypes, are lead vaccine candidates against Ebola, HIV, Tuberculosis and Malaria based on their potent induction

NIAID Data Ecosystem30

Systems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immune gene network: in vitro analysis. Homo sapiens

疫苗免疫学

先天免疫反应

Here we applied a systems approach to define human innate immune signatures following MRKAd5/HIV immunization and to analyze the effects of pre-existing Ad5 immunity. To determine whether vaccine-indu

NIAID Data Ecosystem60

Chronic schistosomiasis suppresses HIV-specific responses to DNA-MVA and MVA-gp140 Env vaccine regimens despite antihelminthic treatment and increases helminth-associated pathology in a mouse model

疫苗免疫学

寄生虫免疫学

Future HIV vaccines are expected to induce effective Th1 cell-mediated and Env-specific antibody responses that are necessary to offer protective immunity to HIV infection. However, HIV infections are

NIAID Data Ecosystem50

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

资源简介：

相关数据集