Crystal structure of dUTPase complexed with substrate analogue methylene-dUTP
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Crystal structure of dUTPase complexed with substrate analogue methylene-dUTP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXY-5'-O-[(S)-HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]URIDINE, Deoxyuridine 5'-triphosphate nucleotidohydrolase Authors: Barabas, O, Kovari, J, Tapai, R, Vertessy, B.G. Deposit date: 2006-07-20 Release date: 2007-07-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. Proteins, 71, 2008
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2006-07-20
