Differential expression of genes in Geobacter sulfurreducens PCA under different electron acceptor and donor conditions

Geobacter sulfurreducens has a complex metabolism that adapts to use electron acceptors at a wide range of redox potentials. In this study, we used RNA-seq to identify genes associated with electron transfer pathways at different redox potentials. By correlating the RNA-seq data with cyclic voltammetry, we associated several multiheme cytochromes with specific electron transfer pathways. Overall design: We sequenced RNA from Geobacter sulfurreducens PCA grown at 7 different conditions in triplicate.