Structure of PAK1 in complex with compound 24
收藏Protein Data Bank Japan2025-07-16 更新2026-05-23 收录
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Structure of PAK1 in complex with compound 24 Descriptor: 3-cyano-N-[3-({6-[(5-cyclopropyl-1,3-thiazol-2-yl)amino]pyrazin-2-yl}amino)bicyclo[1.1.1]pentan-1-yl]azetidine-3-carboxamide, Serine/threonine-protein kinase PAK 1 Authors: Fontano, E, Suto, R.K, Olland, A.M. Deposit date: 2024-08-13 Release date: 2025-04-02 Last modified: 2025-07-16 Method: X-RAY DIFFRACTION (1.898 Å) Cite: Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2. Bioorg.Med.Chem.Lett., 127, 2025
创建时间：
2024-08-13
