Data from: Simultaneous determination of diosmin and hesperidin in combined pharmaceutical preparation by synchronous fluorescence spectrofluorimetric method

Diosmin (DSM) and hesperidin (HSP) binary mixture was analyzed
simultaneously by developing a sensitive, rapid, and simple synchronous
spectrofluorimetric method. In methanol at ∆λ of 100 nm, the relative
synchronous fluorescence intensities (RSFI) of both medications were
measured. It was shown that these intensities were influenced by distinct
experimental factors. The optimization and detailed study of these
parameters were conducted. For DSM and HSP, respectively, the plots of
synchronous fluorescence intensity-concentration were found to be
rectilinear across the ranges of 0.5-5.0 µg/mL and 0.2-3.0 µg/mL. For DSM
and HSP, respectively, 0.107 µg/mL and 0.048 µg/mL were the detection
limits and 0.323 and 0.144 µg/mL were the limits of quantification. The
method described in this study was effectively employed to estimate the
quantities of both drugs present in commercially available mixed tablets.
The results produced using this method were then compared favorably to
results obtained using a different method for comparison.