GEO studies.zip

Here, we reanalysed a total of 27 GEO studies to identify and annotate lung cancer versus normal signatures, as well as single-gene perturbation, and single-drug perturbation signatures. Differential expression within each category was computed using GEO2Enrichr and the Characteristic Direction method. We identified the co-DEGs across different studies within each category, and their upstream regulating kinases and TFs using Expression2Kinases.