Transcriptome analysis of in vitro MSC-derived osteoblastic cells from patients with Primary Myelofibrosis

ChEBI2015-01-10 更新2026-07-21 收录

骨髓纤维化疾病机制

骨相关细胞转录组

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Transcriptome analysis of in vitro MSC-derived osteoblastic cells from patients with Primary Myelofibrosis

创建时间：

2015-01-10

The osteocyte transcriptome is extensively dysregulated in mouse models of Osteogenesis Imperfecta. The osteocyte transcriptome is extensively dysregulated in mouse models of Osteogenesis Imperfecta

成骨不全症分子机制

骨相关细胞转录组

Osteocytes are long-lived, highly interconnected, terminally differentiated osteoblasts which reside within mineralized bone matrix. They constitute about 95% of adult bone cells and play important fu

NIAID Data Ecosystem90

Analysis of hMSC-derived chondrocytes in response to stimulation with SARS-CoV-2 spike proteins

COVID-19研究

骨相关细胞转录组

Previous studies have detected the presence of SARS-CoV-2 viral proteins in bronchial cartilage chondrocytes. We hypothesised that the leakage of viral proteins to local joint tissue was due to virus-

Zenodo2024-09-11 更新30

Skeletal and osteocyte transcriptomic responses to abaloparatide and teriparatide: A comparative study in estrogen-depleted mice

骨质疏松药物机制

骨相关细胞转录组

Osteocytes express parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptors (PTH1R) and respond to the PTHrP analog abaloparatide (ABL) and to the 1-34 PTH fragment teriparatide (TPTD), used to

NIAID Data Ecosystem00

Microarray of Dexamethasone-treated primary chondrocytes identifies downstream targets of glucocorticoid signalling. Mus musculus

骨相关细胞转录组

内皮素信号通路

Background: Glucocorticoids (GCs) are widely used anti-inflammatory drugs. While useful in clinical practice, patients taking GCs often suffer from skeletal side effects including growth retardation a

NIAID Data Ecosystem90

Understanding downstream signaling pathways regulated by miR-34a-5p in articular cartilage by RNA sequencing using miR-34a knock-out mice

骨相关细胞转录组

RNA调控机制

The goal of this study was to determine the role of miR-34a in regulating chondrocyte transcript profiles. Next Generation Sequencing of total RNA extracted from mouse KO and WT chondrocytes revealed

NIAID Data Ecosystem10

Transcriptome analysis of in vitro MSC-derived osteoblastic cells from patients with Primary Myelofibrosis

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