JAK2 crystal structure in complex with Compound 13
收藏Protein Data Bank Japan2024-10-16 更新2026-05-24 收录
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JAK2 crystal structure in complex with Compound 13 Descriptor: (3R)-3-cyclopentyl-3-[(4M)-4-{5-methyl-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-1H-pyrazol-1-yl]propanenitrile, 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2 Authors: Miller, S.T, Ellis, D.A. Deposit date: 2023-02-16 Release date: 2023-06-21 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility. J.Med.Chem., 66, 2023
创建时间：
2023-02-16
