Role of viral pattern recognition pathways in mediating poly I:C-induced immunosuppression.
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Age- and sex-matched Cardif−/−, Tlr3−/−, Cardif−/−/Tlr3−/− and WT animals were administered i.n. poly I:C for 3 days, followed by i.t. S. pneumoniae (1×104 CFU). Animals were sacrificed and lungs collected at 48 hours after bacterial infection for enumeration of CFU. **, pCardif−/−/Tlr3−/− n = 4–7/group. All other comparisons were not significant. Data is representative of 2 separate experiments.
创建时间：
2016-02-24
