Immature Granulocytes As Biomarker In Peripheral Blood For Sub-acute Inflammation In Early Diagnosis of Lower Extremity Arterial Thrombosis

Early diagnosis and treatment are critically important in terms of prognosis in subacute arterial thrombosis. The aim of our study is to investigate whether immature granulocytes are useful in the early diagnosis of subacute artery thrombosis. This retrospective study was conducted in a single center between 2019 and 2021 A total of 99 patients with lower extremity chronic peripheral arterial disease were included in the study. Among these patients, 27 patients with subacute artery thrombosis were included in SAT group. The remaining 72 patients were included in control group. The blood samples of the patients in both groups, belonging to the first application and before receiving any treatment, were analyzed. CBC parameters calculated with automatic hematological analyzer between groups were compared statistically. Our study showed that immature granulocytes can be very useful in the diagnosis of SAT, with a sensitivity of 81% and a specificity of 90%.