Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency
收藏NIAID Data Ecosystem2026-03-08 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
应用场景:
创建时间:
2013-10-18
相关数据集
Disruption of higher order nuclear condensates by a dominant negative FOXN1 mutation causes immunodeficiency. Disruption of higher order nuclear condensates by a dominant negative FOXN1 mutation causes immunodeficiency
The transcription factor FOXN1 acts in a gene-dosage sensitive way as a master regulator of thymic epithelial cell development and maintenance enabling effective thymopoiesis. Its autosomal recessive
NIAID Data Ecosystem80
DataSheet_1_Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience.pdf
PurposeUpregulation of type I interferon (IFN) signaling has been increasingly detected in inflammatory diseases. Recently, upregulation of the IFN signature has been suggested as a potential biomarke
NIAID Data Ecosystem40
RNA-seq profiling of resting naive and CD27bright memory B cells and in vitro activated CD27bright memory B cells reveals differences in B-cell activation patterns in common variable immunodeficiency (CVID)
To investigate the transcriptional differences during resting state and B-cell activation in healthy donors and patients with CVID, we sorted naive B cells and CD27bright memory B cells from the two g
NIAID Data Ecosystem30
Transcriptional analysis of whole blood and PBMCs from human HOIP deficiency patients
LUBAC (linear ubiquitin assembly complex) consists of HOIP, HOIL1 and SHARPIN. HOIP deficiency has been characterized by immunodeficiency, autoinflammation and amylopectinosis. To explore the molecula
NIAID Data Ecosystem60
Ablation of ZBTB24 in hematopoietic cells in mice results in antibody deficiency that mimics ICF syndrome
ICF syndrome, a rare autosomal recessive disorder characterized by immunodeficiency, centromeric instability and facial anomalies, is caused by mutations in DNMT3B, ZBTB24, CDCA7 or HELLS. In this stu
NIAID Data Ecosystem40



