Stability data for palmitoylethanolamide (PEA, 1) and compounds 3–5, 7–9, 19–24, 26–31, 33.
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a Values expressed as percent remaining after 6 h of incubation at 37°C in PBS buffer pH 7.4.
bt1/2 values calculated from pseudo first-order rate constants; mean ± SD, n = 3.
c PEA basal level in 80% rat plasma = 20.1 ± 5.6 nM.
d See Fig 2.
e Percent remaining after 6 h incubation at 37°C in rat plasma.
f Percent remaining after 2 h incubation at 37°C in rat liver homogenate.
g Referred to (R)-α-methyl-PEA.
Stability data for palmitoylethanolamide (PEA, 1) and compounds 3–5, 7–9, 19–24, 26–31, 33.
创建时间:
2015-12-03



