Set of Data from "Selective targeting of striatal parvalbumin-expressing interneurons for transgene delivery" https://doi.org/10.1016/j.jneumeth.2021.109105
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PV<sup>Cre</sup> (+/+) mice were injected in the right striatum with AAV2/1-hsyn-FLEX-eGFP AAV2/9-CBA-FLEX-eGFP or AAV2/9-hsyn-FLEX-eGFP vectors. Two weeks after, cells were manually counted by a blind observer on 2D maximal intensity projections of confocal images transformed into the tiff format using the Multi-point tool in ImageJ. The GraphPad .pzfx files show the quantitative anaylsis of the proportion of GFP+ cells which were PV+ (specificty) , the proportion of PV+ cells which were GFP+ (efficiency), the proportion of PV+ cells in the injected striatum relative to to the injected striatum of PV<sup>Cre</sup> (+/+) mice (absence of vector toxicity) and the proportion of PV+ cells in the striatum of PV<sup>Cre</sup> (+/+) mice versus wt mice.
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2023-05-01



