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Supplementray Figures and Supplementary Data 1

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Figure S1. The mechanical diagram of the study.A mechanistic diagram of PPARγ signaling regulating hypoxia-induced ferroptosis in HTR-8/Svneo cells with/without rosiglitazone intervention was built by Figdraw software. Figure S2. Uncropped blots. Figure S3. Pearson correlation analysis.Correlation analysis of PPARγ with Nrf2 levels and ferroptosis-related indicators in PE was performed. Figure S4. Expression verification of GPx4, ACSL4, FASN, ACC1, and SCD1.(a) GPx4 mRNA and protein levels. *P<0.05 vs the NC group, one-way ANOVA. (b) PPARγ binding to SREBP1 and Nrf2 was predicted using the online software STRING. (c) ACSL4 protein levels. (d) FASN, ACC1, and SCD1 levels. (n=3). *P<0.05 vs the NC group, &P<0.05 vs the Hypoxia group, and @P<0.05 vs the Hyp + si-SREBP1 group, two-way ANOVA. Supplementary Data 1. Raw data and original images of this study.
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2023-04-17
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