five

DYRK1A complex with DYR530

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Protein Data Bank Japan2024-11-27 更新2026-04-25 收录
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DYRK1A complex with DYR530 Descriptor: (4P)-4-{(3M)-3-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]-2-methyl-3H-imidazo[4,5-b]pyridin-5-yl}pyridin-2-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, GLYCEROL, ... Authors: Montfort, W.R, Basantes, L.E. Deposit date: 2023-06-06 Release date: 2024-05-15 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B. J.Med.Chem., 67, 2024
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2023-06-06
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