Crystal structure of human Sirtuin 2 in complex with a selective inhibitor
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of human Sirtuin 2 in complex with a selective inhibitor Descriptor: 2-[[3-(2-phenylethoxy)phenyl]amino]benzamide, NAD-dependent protein deacetylase sirtuin-2, ZINC ION Authors: Mellini, P, Itoh, Y, Tsumoto, H, Li, Y, Suzuki, M, Tokuda, N, Kakizawa, T, Miura, Y, Takeuchi, J, Lahtela-Kakkonen, M, Suzuki, T. Deposit date: 2017-08-09 Release date: 2017-09-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Potent mechanism-based sirtuin-2-selective inhibition by anin situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site. Chem Sci, 8, 2017
创建时间：
2017-08-09
