Crystal structure of wild-type HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 5i3
收藏Protein Data Bank Japan2025-06-11 更新2026-05-23 收录
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Crystal structure of wild-type HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 5i3 Descriptor: (2E)-3-[4-({2-[(1-{[4-(methanesulfonyl)phenyl]methyl}piperidin-4-yl)amino]pyrido[2,3-d]pyrimidin-4-yl}oxy)-3,5-dimethylphenyl]prop-2-enenitrile, 1,2-ETHANEDIOL, MAGNESIUM ION, ... Authors: Rumrill, S, Ruiz, F.X, Arnold, E. Deposit date: 2024-01-29 Release date: 2025-05-07 Last modified: 2025-06-11 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles. Sci Adv, 11, 2025
创建时间：
2024-01-29
