Effect of PML/RARa on the transcriptome of maturing myeloid populations in vivo

ChEBI2015-06-24 更新2026-07-12 收录

急性早幼粒细胞白血病机制

浆细胞转录组学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-54474 数据链接链接失效反馈

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Effect of PML/RARa on the transcriptome of maturing myeloid populations in vivo

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2015-06-24

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

肿瘤免疫微环境

浆细胞转录组学

The role of myeloid cells in supporting cancer growth is well established. Most work has focused on myeloid-derived suppressor cells (MDSC) that accumulate in tumor-bearing animals, but tumor-associat

NIAID Data Ecosystem70

Intrinsic toxicity of LCDD monoclonal Ig free light chain on plasma cells (PC)

轻链沉积病机制

浆细胞转录组学

We analyzed the transcriptome (RNA-seq) of mouse plasma cells (PC) expressing a human Ig light chain from a patient suffering light chain deposition disease (LCDD) as compared to control plasma cells

NIAID Data Ecosystem50

Gene expression variation in lymphocyte subpopulations in response to low dose of ionizing radiations . Homo sapiens

辐射生物剂量

浆细胞转录组学

Lymphocytes are the standard cell of a majority of biodosimetry approaches because of their availability and radiosensitivity. But progresses remain to be performed to bring down the minimum threshold

NIAID Data Ecosystem40

Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice

急性早幼粒细胞白血病机制

造血干细胞功能

Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid p

NIAID Data Ecosystem60

Effect of recombinant Shh on gene expression of primary rat nucleus pulposus cells

浆细胞转录组学

Shh信号通路抑制

In order to study the effect of recombinant Shh (rShh) on nucleus pulposus cells, primary nucleus pulposus cells from SD rats were obtained.Then, nucleus pulposus cells were treated with rShh at 200 n

NIAID Data Ecosystem50

Effect of PML/RARa on the transcriptome of maturing myeloid populations in vivo

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