HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor Descriptor: (2R,3R,4R,5R)-2,5-BIS[(2,3-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXAN EDIAMIDE, POL POLYPROTEIN Authors: Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. Deposit date: 2004-08-10 Release date: 2004-12-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem., 271, 2004
创建时间：
2004-08-10
