five

human STING With agonist HB3089

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Protein Data Bank Japan2024-06-19 更新2026-05-23 收录
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human STING With agonist HB3089 Descriptor: 1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methyl-1H-furo[3,2-e]benzimidazole-5-carboxamide, Stimulator of interferon genes protein Authors: Wang, Z, Yu, X. Deposit date: 2022-09-07 Release date: 2022-12-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation. Cell Discov, 8, 2022
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2022-09-07
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