Effect of Lemd2 p.L13R mutation on gene expression in mouse hearts at 9 months old

To determine transcriptional changes caused by the Lemd2 mutation and to gain insights into the mechanisms responsible for the phenotype of arrhythmic cardiomyopathy we performed RNA-sequencing in 9 months old mouse hearts Overall design: Comparative gene expression profiling analysis of RNA-seq data for 9 months old wild-type (WT) and Lemd2 p.L13R knock-in (KI) mouse hearts