Cu-Catalyzed Remote Transarylation of Amines via Unstrained C–C Functionalization
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https://figshare.com/articles/dataset/Cu-Catalyzed_Remote_Transarylation_of_Amines_via_Unstrained_C_C_Functionalization/13344279
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资源简介：
Remote
arylation of amines via C–C bond functionalization
has not been reported yet. Herein, we develop the γ-transarylation
of amines through the cleavage of unstrained C–C bond enabled
by copper catalysis under mild conditions, representing the example
of utilization of unstrained C–C bond for metal-catalyzed C–C
cross-coupling. Mechanistic investigations reveal that the redox-neutral
reaction undergoes an intercepted radical pathway to cleave the Csp2–Csp3 bond, followed
by the combination with copper-catalyzed arylation reaction in the
presence of aryl boronic acid to construct a new Csp2–Csp3 bond.
创建时间：
2020-12-07
