Wasl

Predicted to enable cytoskeletal protein binding activity and identical protein binding activity. Involved in dendritic spine morphogenesis and regulation of postsynapse organization. Acts upstream of or within several processes, including actin cytoskeleton organization; response to bacterium; and spindle localization. Located in actin cap and lamellipodium. Is active in glutamatergic synapse. Is expressed in brain; genitourinary system; liver; and spleen. Used to study atopic dermatitis. Orthologous to human WASL (WASP like actin nucleation promoting factor). [provided by Alliance of Genome Resources, Nov 2024]

预测具有细胞骨架蛋白结合活性和相同蛋白结合活性。参与树突棘形态发生和突触后组织的调节。在多个过程的上游或其中发挥作用，包括肌动蛋白细胞骨架组织；对细菌的反应；以及纺锤体定位。位于肌动蛋白帽和质膜。在谷氨酸能突触中活性。在脑、泌尿生殖系统、肝脏和脾脏中表达。用于研究特应性皮炎。与人WASL（WASP样肌动蛋白核化促进因子）同源。[由基因组资源联盟提供，2024年11月]