scPII Benchmarking Results
收藏资源简介：
Contains all the benchmarking results performed on 16 CCLE scRNA-seq pan-cancer datasets according to the following benchmarking schemes - Testing 4 GRNS construction algorithms (Pearson, Spearman, GRNBoost2, pcNet) to evaluate the performance of scPII. Testing explained variance cutoff for optimal performance of scPII with GRNBoost2-derived GRNs. Testing runtimes and accuracy of scPII against virtual KO algorithms (GenKI and scTenifoldKnk) in 3 CCLE scRNA-seq cell lines. File naming convention CCLE_Benchmark - scPII summary files - {algorithm}_{CellLine}_{InteractionCutOff}_{ProportionOfExplainedVariance}_scPII_Summary.csv Median gene KO effect of top 50 genes by algorithm - {algorithm}_GeneKOEffect_{InteractionCutOff}_{ProportionOfExplainedVariance}_Medians_P.csv VirtualKO_Benchmark - scRNA-seq-derived-GRN used for benchmarking - {CellLine}_{algorithm}_GRN.npz Summary files for each algorithm - {CellLine}_{algorithm}_Summary.csv Compiled scores from three algorithms - {CellLine}_Benchmark_Data.csv
