Single-cell RNA-sequencing of intratibial LLC cancer model in DMP1-Cre Mfn2-/- mice, DMP1-Cre Rhot1-/- mice, and wild-type mice.
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https://www.ncbi.nlm.nih.gov/sra/SRP430441
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资源简介：
We injected LLC1 cells into the tibia of DMP1-Cre Mfn2-/- mice, DMP1-Cre Rhot1-/- mice, and wild-type mice to study the changes in the cellular composition of the cancer microenvironment after knockout of Mfn2 or Rhot1 in osteocytes. Overall design: LLC1 cells were injected intra-tibially into DMP1-Cre Mfn2-/- mice, DMP1-Cre Rhot1-/- mice, and wild-type mice. 14 days later tumor-bearing tibia were dissected and enzymatically dissociated into single cell suspension. Live cells were analyzed using scRNAseq (3 tumors from 3 mice mixed 1:1:1 for each group).
创建时间：
2024-01-25
