Congenital talipes equinovarus (CTEV) is one of the most common congenital limb defects in children, which is a multifactorial and complex disease that associates with many unknown genetic, social-dem

NIAID Data Ecosystem30

Calycosin as a novel PI3K activator reduces inflammation and fibrosis in heart failure through AKT-IKK/STAT3 axis. Calycosin as a novel PI3K activator reduces inflammation and fibrosis in heart failure through AKT-IKK/STAT3 axis

心肌炎症与纤维化

PI3K/AKT信号通路

Aim: Inflammation and fibrosis have been shown to be critical factors in heart failure (HF) progression. Calycosin (Cal) is the major active component of Radix astragali and has been widely used to tr

NIAID Data Ecosystem30

Ginsenoside Rg3 and sorafenib combination therapy relieves the hepatocellular carcinomaprogression through regulating the HK2-mediated glycolysis and PI3K/Akt signaling pathway

肝细胞癌

PI3K/AKT信号通路

Hepatocellular carcinoma (HCC) is the most common pathological type of primary hepatic carcinoma. This study investigated the effects of ginsenoside Rg3 (Rg3) and sorafenib (SFN) combination therapy o

DataCite Commons2024-02-13 更新60

Transcriptomic study of PIK3D transfected-Huh7 cells

肝癌转录组

PI3K/AKT信号通路

The isoform delta of class I Phosphoinositide 3-kinase (PI3Kδ) is expressed primarily in hematopoietic cells, and its inhibitor, idelalisib, is approved for the treatment of leukemia and lymphoma. PI3

NIAID Data Ecosystem30

Correlation between AKT activation (pAKT) and expression of the different members of the PI3K pathway patients with OC.

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