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Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C‑Glycosides

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_Stereochemically_and_Skeletally_Diverse_Fused_Ring_Systems_from_Functionalized_i_C_i_Glycosides/2407531
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A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl ester for further diversification via amine capping and amide coupling. Scaffold diversity was evaluated in comparison to previously prepared scaffolds by a shape-based principal moments of inertia (PMI) analysis.
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2016-02-19
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