Crystal structure of DoxA in complex with reaction intermediate DHD
收藏Protein Data Bank Japan2026-03-25 更新2026-05-24 收录
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Crystal structure of DoxA in complex with reaction intermediate DHD Descriptor: (7~{S},9~{S})-7-[(2~{R},4~{S},5~{S},6~{S})-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4-methoxy-6,9,11-tris(oxidanyl)-9-[(1~{R})-1-oxidanylethyl]-8,10-dihydro-7~{H}-tetracene-5,12-dione, Cytochrome P-450 monooxygenase DoxA, PROTOPORPHYRIN IX CONTAINING FE Authors: Kim, R.Q, Metsa-Ketela, M. Deposit date: 2025-08-28 Release date: 2025-12-24 Last modified: 2026-03-25 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA. Nat Commun, 17, 2026
创建时间：
2025-08-28
