Functional screening of DNAJB6 for machine learning-guided protein engineering
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1240288
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资源简介：
A high-throughput screen of the human chaperone DNAJB6 to enhance its ability to rescue a FUS-induced toxic phenotype in yeast. Data from thousands of variant-score pairs were used to train a machine learning model, enabling the design of hyperactive DNAJB6 variants under various constraints.
创建时间：
2025-03-21
