Recruitment of mitotic centrosome proteins and complexes
收藏reactome.org2025-03-24 收录
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The mitotic spindle becomes established once centrosomes have
migrated to opposite poles and the nuclear envelope has broken down. During this stage, interphase centrosomes mature into mitotic centrosomes
recruiting additional gamma TuRC complexes and acquiring mitosis-associated centrosomal proteins including NuMA, Plk1 and CDK11p58 (reviewed in Schatten 2008; Raynaud-Messina and Merdes 2007).
在中心体迁移至相对的两极并核膜解体之后,有丝分裂纺锤体得以形成。在此阶段,间期中心体成熟为有丝分裂中心体,招募额外的γTuRC复合物,并获取与有丝分裂相关的中心体蛋白,包括NuMA、Plk1和CDK11p58(详见Schatten 2008年综述;Raynaud-Messina和Merdes 2007年研究)。
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