Evidence for toxic CAG trinucleotide repeats contributing to Huntington's disease though RNA interference
收藏NIAID Data Ecosystem2026-03-14 收录
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Mutant huntingtin CAG trinucleotide repeat mimetic hairpins are loaded into the RISC and kill cells through RNAi Overall design: Striatum of mouse brains of wt, 250CAG and 450CAg mice was lized. Subsequently, Ago protein associated short RNAs were pulled down using a GW182 peptide and subjected to smRNA Seq
创建时间：
2023-01-26
