Identification of mono-ADPr readers by multilevel chromatin proteomics
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https://www.omicsdi.org/dataset/pride/PXD037026
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资源简介：
We performed multilevel proteomics to identify mono-ADPr readers. Pulldowns using ADPribosylated peptides and nucleosomes, analysis of the chromatin proteome using targeted modulations of the ADPr system (H2O2 treatment, ARH3 KO, HPF1 KO). We reveal multiple mono-ADPr readers, including RNF114, a ubiquitin ligase recruited to DNA lesions through a zinc finger domain.
创建时间：
2023-04-28
