Transcriptome analysis of primary normal fibroblasts and matched cancer associated fibroblasts
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https://www.ncbi.nlm.nih.gov/sra/SRP358911
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To get an insight into the mechanisms for CAF-supported metastasis in breast cancers, we performed RNA-sequencing (RNA-seq) analysis with seven pairs of primary NFs and CAFs.Gene set variation analysis (GSVA) showed significant upregulated expression of genes enriched with cancer metastasis-associated signaling pathways. Besides, we identified CAF signature genes, which have similar patterns in several of these primary CAFs. Overall design: The mRNA profiles of seven pairs of primary normal fibroblasts and matched cancer associated fibroblasts
创建时间：
2022-12-10
