Cell surface expression of BCMA, TACI, BR3 and comparative sensitivity of various cancer cell lines to BLyS-gel.

*Values determined by flow cytometry and presented as (MFI 1° Ab+MFI 2°Ab) – (MFI 2° Ab only)**sensitivity determined by incubation with 500 pM BLyS-gel for 72 hrs. Cell viability determined as described in Materials and Methods. Viability reduced by >20% = +; >40% = ++; >60% = +++; >80% = ++++(?) cell line possibly mis-characterizedAbbreviations: MFI, mean fluorescense intensity; MCL, mantle cell lymphoma; DLBCL; diffuse large B cell lymphoma; BL, Burkitt's lymphoma; MM, multiple myeloma; BCP-ALL, B cell precursor-acute lymphoblastic leukemia; B-CLL, B cell chronic lymphocytic leukemia; ND, not determined